Searchable abstracts of presentations at key conferences in endocrinology

ea0011oc26 | Diabetes and metabolism | ECE2006

Neuropeptide S is a novel peptide which potently stimulates the hypothalamo-pituitary-adrenal axis and inhibits food intake

Smith KL , Patterson M , Dhillo WS , Patel SR , Semjonous NM , Gardiner JV , Ghatei MA , Bloom SR

Neuropeptide S (NPS) is a recently discovered peptide shown to be involved in the modulation of arousal and fear responses. It has also been shown that lateral ventricle administration of NPS causes a significant decrease in food intake. Neuropeptides involved in the modulation of arousal have been shown to be involved in the regulation of the hypothalamo-pituitary adrenal (HPA) axis and food intake.Objective: To examine the effect of NPS on the regulati...